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Does DHM Really Reduce Hangovers?

    Let’s learn about Dihydromyricetin!

    Dihydromyricetin, DHM or Amperopsin, is an herbal hangover remedy, a special kind of flavonoid extracted from the oriental raisin tree. DHM is used as a traditional medicine for alcohol-related illnesses in parts of Asia and has recently become popular in the West.

    Dihydromyricetin is characterized by its anti-alcoholic effect. It reduces hangover symptoms by promoting alcohol metabolism and enhancing liver function. DHM is also characterized by its antioxidant, anti-inflammatory, and anti-tumor effects. Let’s learn more about this powerful anti-alcohol extract in this article.

    Figure 1. Does DHM Really Reduce Hangovers?

    Does DHM really relieve hangovers?

    Alcohol-related illnesses have plagued us for many years. According to the World Health Organization, alcohol is responsible for 5.1% of the global burden of illness and injury [1]. Needless to say, drinking alcohol can trigger unpleasant feelings such as headaches, nausea, vomiting, anxiety, clumsiness, and speech impediments.

    Dihydromyricetin alleviates these symptoms in the following ways:

    1. DHM lowers the alcohol level by improving the performance of two alcohol intake enzymes. Excessive alcohol consumption means excessive production of toxic ethanol and acetaldehyde, thus increasing the burden on the liver. DHM helps produce more alcohol breakdown enzymes (ADH and ALDH) and assist to increase their activities.
    2. Dihydromyricetin reduces toxic substances in the liver, which could avoid the possibility of liver damage. DHM could not only reduce the burden on the liver by breaking down ethanol and acetaldehyde more quickly but also reduce hepatic fat accumulation and inflammatory factors. Fat increases the risk of liver diseases such as cirrhosis. Inflammatory factors such as cytokines cause cellular damage in the liver and other organs. Such damage is avoided by DHM.

    Is Dihydromyricetin safe?

    Dihydromyricetin is fairly safe to take. First, in Asia, it has been used for hundreds of years as a natural hangover remedy. And no side effects have been reported in scientific studies in animals and humans. Plus, you can find thousands of positive reviews about hangover supplements containing DHM. However, please use DHM appropriately and drink wisely.

    How is Dihydromyricetin used? 

    Based on current animal studies, the recommended dose of dihydromyricetin is 80-1200 mg, and the optimal dose of DHM is approximately 300 mg. Nevertheless, healthier drinking habits are more effective. Drink more water, and eat something before dining out. 

    The best time to use Dihydromyricetin varies. If you are using DHM prophylactically, it is recommended to take the herbal dietary supplement 30 minutes before drinking alcohol. If you’re taking it for hangover relief, that’s the perfect time. DHM works more effectively during sleep.


    The article above details the effects, uses, and safety of dihydromyricetin. We hope that you now have a better understanding of DHM and its effects on drunkenness. Stanford Chemicals Company (SCC) is a leading provider of the most effective hangover treatments. For more information, please check our website.

    Furthering Reading: Everything You Need to Know About Dihydromyricetin


    [1] World Health Organization (2022, May 9). Alcohol. Retrieved January 16, 2023, from